Myelodysplastic Syndromes (MDS)
- Registration Closed
Omar Abdel-Wahab, MD
Memorial Sloan Kettering Cancer Center
I am a hematologist/oncologist, Associate Professor at Memorial Sloan-Kettering Cancer Center (MSK) and Weill Cornell College of Medicine, and Director of the MSK Center for Hematologic Malignancies. My clinical areas of expertise are in myeloid malignancies, chronic lymphocytic leukemia, and rare forms of leukemias including hairy cell leukemia, CMML, BPDCN, and histiocytoses. My research laboratory is focused on the functional understanding of genetic alterations in patients with chronic myeloid and lymphoid leukemias. One of our main areas of interest is in understanding the biological and therapeutic significance of epigenetic and transcriptional alterations in patients with myelodysplastic syndromes. As such, we have a focused interest in understanding the role of mutations in RNA splicing factors which are amongst the most common genetic alterations in this disease. We are interested in understanding what cellular pathways are perturbed by oncogenic alterations in RNA splicing factors as well as developing means to target these changes therapeutically. Our work is currently funded by the Leukemia & Lymphoma Society, the National Institute of Health, the U.S. Dept. of Defense, the American Society of Hematology, the EvansMDS Foundation, and the Taub Foundation for MDS Research, amongst others.