Waldenström Macroglobulinemia (WM)
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Stephen Ansell, MD, PhD
Mayo Clinic Minnesota
Stephen M. Ansell, M.D., Ph.D. is a consultant in the Division of Hematology, Department of Internal Medicine at Mayo Clinic in Minnesota. Dr. Ansell currently serves as chair of the Mayo Clinic Lymphoma Disease-Oriented Group and chair of faculty development and recruitment for the Division of Hematology. He joined the staff of Mayo Clinic in 1999 and holds the academic rank of professor of medicine, Mayo Clinic Alix School of Medicine.
Dr. Ansell earned his M.B., Ch.B., and Ph.D. degrees at University of Pretoria in Pretoria, South Africa, where he also completed an internship in internal medicine and surgery, a residency in internal medicine, and a fellowship in medical oncology. Dr. Ansell continued his education at University of the Witwatersrand in Johannesburg where he was a registrar in internal medicine. He then came to the United States and completed a residency in internal medicine and then a fellowship in hematology/oncology at Mayo Clinic.
Dr. Ansell’s research focuses on investigating the phenotype and activity of intratumoral T cells and developing strategies to modulate the T-cell infiltration in B-cell lymphoma. Further areas of research interest include the development of biologic therapies for non-Hodgkin's lymphoma, Hodgkin’s disease and Waldenstrom macroglobulinemia. The current strategies being developed include the use of novel antibodies and cytokines, the use of targeted therapies, and the development of strategies to inhibit signaling through receptors that promote the survival of malignant B cells. The utility of these strategies is being tested in early-phase clinical trials.
Dr. Ansell is frequently invited to give presentations on his research to both national and international audiences, and has published in high-impact scientific journals. He is associate editor of the American Journal of Hematology and serves on the Editorial Board for Blood, Blood Cancer Journal, JAMA Oncology and Journal of Clinical Oncology. He is often a reviewer for various scientific journals.
In recognition of his work, Dr. Ansell has received awards and honors, including the New Investigator Award, the Teacher of the Year Award in the Hematology Fellowship Program, and the Department of Medicine Research Award for Landmark Contributions to the Literature.
In addition to his research activities, Dr. Ansell is active in education and mentoring. He holds full faculty privileges in Biomedical Engineering at Mayo Clinic Graduate School of Biomedical Sciences.
Dr. Ansell also serves on the Scientific Advisory Board of the Leukemia& Lymphoma Society (LLS), the Lymphoma Research Foundation (LRF) and the International Waldenstrom Macroglobulinemia Foundation (IWMF).